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SweetTi3 t1_j0zvn2h wrote

As far as I know ( and I could be wrong )The combination is a great vasodilator. In some studies , nicotine actually doubled the rate in which the body gets rid of the caffeine. The combination can trigger anxiety in some individuals.

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TryhardHS t1_j12n143 wrote

It’s definitely a vasoconstrictor. I have arteriovenous malformations that ache when I take vasodilators (including alcohol). Caffeine reduces pain from the malformations due to being a vasoconstrictor. I can feel it working.

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