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whyyou- t1_j1q06cz wrote

Depends; ABO incompatibility is not really an issue, Rh incompatibility is more serious but only if the mother negative and has been previously exposed to Rh(+) antigen (a previous pregnancy, blood transfusions). If the mother has been exposed and mother / baby are incompatible (mother negative, baby positive) it can lead to hemolytic disease of the fetus an autoimmune disease that breaks down the fetus blood cells and can be so severe to cause intrauterine death.

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kkngs t1_j1q781q wrote

Right. There is a shot they give to mothers in this situation, called RhoGAM, to help prevent the moms developing permanent antibodies.

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nicnoog t1_j1ro7o6 wrote

Shot is only for Anti-D, I unfortunately am anti-K - it's quite the faff when pregnant.

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[deleted] t1_j1rsp7r wrote

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No-Owl-295 t1_j1rg688 wrote

Which only works if her body did not form antibodies yet. If she already has antibodies and the fetus survives the first few weeks, they usually need several intra-uterine blood-transfusions.

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[deleted] t1_j1rp4ab wrote

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Hockeygoalie35 t1_j1tekzy wrote

I was an RH Disease baby. Needed several blood transfusions while still in the uterus, was born 10 weeks premature for further transfusions.

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