Submitted by salt-the-skies t3_zq4tw7 in askscience
5J7XM33IXN4XCQI6B2BB t1_j0zm94y wrote
I suspect it's effectively impossible to produce the kind of answer you are looking for. In order to make a determination that a species went extinct solely due to predation, we would need to have observed it very closely, which effectively excludes your qualifier "free of human interference." Also, you can't really attribute extinction solely to any one factor, unless you mean, "was the last individual killed by as predator, in its natural environment without human interaction of any kind?", or some other really specifically qualified question.
I guarantee that many species have gone extinct in large part due to pressure from predation. The Lotka–Volterra equations describe an idealized predator-prey dynamic where the populations have a stable oscillation without a possibility of extinction. In reality, many predation dynamics come so close to prey extinction that small fluctuations at the right time can reduce the prey population below a viable size.
Keep in mind, that natural selection can only act on existing variation in a population, so a prey species likely won't even have the ability to respond in a meaningful way to a significant predatory adaptations. This will normally just alter the dynamic and result in more extreme oscillations, but not necessarily result in extinction.
Game_Minds t1_j0zth32 wrote
Precisely- we have really good models for "natural" dynamics like predator introduction that should result in extinctions from predation pressure. And there are lots of examples of that happening due to direct human interference or climate change. But it's probably not broadly possible to produce an example like what OP might be looking for, since any extinctions observed by modern science are influenced by human activities at every level
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