Submitted by One-Garden-1294 t3_z0cmd1 in askscience
Responsible_Ad2463 t1_ix79k8x wrote
Reply to comment by BZRich in Do NSAIDs reduce neuroinflammation? by One-Garden-1294
Even naprozen ? For kidney pain
EmilyU1F984 t1_ix7ljd2 wrote
Naproxen has cox2 inhibitory effects, if thus increases cardiovascular health risks. And like any nsaid it can cause chronic interstitial nephritis (kidney damage) in long term and or high dose use.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869646/ for the kidney specific part.
This is true for aspirin, ibuprofen, naproxen, Diclofenac etc.
BZRich t1_ix8jufs wrote
Unfortunately yes. naproxen is very effective and has a long half life but it is not free from side effects.
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