phriendlyphellow t1_ivpyn4r wrote
Reply to comment by mayonnace in Does the dna of transplanted organs (organic material) change after the recipient successfully recovers? by theZoid42
And to your point about gene therapy…
This is a hot area of synthetic regenerative biology. Instead of dealing with donor matching and immunosuppression, what if you could extract a patient’s cells, reprogram them to a pluri- or multi- potent state, use gene editing tools like CRISPR to correct any degenerative genetic defect, grow the patients pool of cells, infuse them into a decellularized extracellular matrix (ECM) of an organ they need, and cisplant (as opposed to transplant, because it’s their own cells).
Theoretically possible and a number of these techniques have made it past the proof of concept stage.
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