Complicated: just because the genome has been sequenced doesn’t mean that we all have the same genes codes. It’s just to be used as a reference in order to find other mutations and have a rough idea of what the genome should look like.

One of the problems with the current model is that it fails to account for natural variation in terms of race or location. There’s a reason each country has its own program for genome sequencing, and I think England is doing it the best by randomly asking people to join rather than self report bcus that way you get a wider variety of variations.

In general, as a sidebar, The HGP also doesn’t account for the exome or other environmental factors. The variations in our genes are sometimes just base pairs but that mutation can be very significant, so having a “healthy” reference or protein can help us understand why it happens.