davedeoreo t1_ivgtzqx wrote
Reply to comment by heresacorrection in If the Human Genome Project represents a map of the genome of a few individuals, why is this relevant to humans as a whole if everybody has different genetics? by bjardd
Username checks out I guess, lol. Could you please shed some light on this then? It's my understanding that the reference genome is created using contigs via overlapping reads - does this not mean it's a consensus sequence on the most common nucleotide at each position? Or is it more that long stretches which are generally similar enough to overlap aid in determining location along the genome?
Also T2T is more recent right? I was mainly referring to the 2003 method in my first comment.
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