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erublind t1_isj48qx wrote

Reply to comment by marieterna in Are proteins used inside the nucleus of eukaryotic cells synthesised outside the nucleus (like other proteins) and transported back inside the nucleus? I had things like histones and transcription factors in mind when I thought of this question. Many thanks by scuba_dooby_doo

Membrane proteins of the inner nuclear membrane (INM) was part of my research project, once upon a time. The nuclear pore complex has eight sided symmetry, with a central channel and eight peripheral routes, probably for membrane proteins. Every mitotic cycle, the nuclear membrane kind of melts into the er and is reformed around the daughter nuclei, probably directed by ranGTP gradient and proteins of the INM.

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marieterna t1_isjun7f wrote

Oh wow, that’s really interesting. Do you have any readings about that?

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