WorldThrombosisDay t1_irrz60w wrote on October 10, 2022 at 4:17 PM

Reply to comment by Cultural-Twist7546 in AskScience AMA Series: I am Prof. Beverley Hunt, OBE, and I am a hematologist in London, England. I am also chair of the World Thrombosis Day Steering Committee. I am here to talk about why MTHFR testing is unnecessary and can cause misinterpretation. AMA! by AskScienceModerator

The MTHFR variant is not related to increased risk of venous thromboembolism (VTE). There are six tests that are definitely associated with increased risk of venous thromboembolism and should be on any inherited thrombophilia testing.

They are: measuring functional antithrombin levels, protein C levels, protein S levels, looking for Prothrombin 22 10, measuring fibrinogen levels, and lastly doing a test for Factor V Leiden.