Submitted by parrotlunaire t3_ybxoct in askscience
slouchingtoepiphany t1_itj6ump wrote
Many, if not most, drugs may elicit an immune response (hypersensitivity reaction), if you look at the adverse reactions sections of the package inserts for most drugs, you'll see a listing of the events that have been reported in clinical trials and the incidences at which they occurred.
parrotlunaire OP t1_itj7g7v wrote
Yes it can happen but it is quite rare, right? I may be wrong but it seems like 95+% of the time there is no problem.
Zkenny13 t1_itj8am3 wrote
Because they're designed that way. They can trigger a response using the improper dosage or the bad response to the drug outweighs the benefits (think chemo drugs).
Also some responses are really common but can be ignored or fixed by other medications. Such as many people get really itchy on opiates but the pain relief fat outweighs the uncomfortable itching or people just take an antihistamine with it.
Drugs are tested and tested and tested then they start human trials and they're tested again or at least usually.
slouchingtoepiphany t1_itj9onj wrote
The occurrence of immune mediated evemts is low because companies don't want to develop drug treatments if there's a stong likliehood that it will trigger an immune reaction in patients.
parrotlunaire OP t1_itjahjm wrote
Ah, that makes sense, thanks!
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