Submitted by [deleted] t3_xxa73t in askscience
The_Scarf_Ace t1_irbfc3y wrote
Reply to comment by penicilling in Why do some antihistamines make you sleepy? by [deleted]
If both act on acetylcholine receptors, then what would be the effect of mixing antihistamines with nicotine?
WittyUnwittingly t1_irbhanu wrote
Anecdotally, the nicotine rush is more intense coming off a dose of Benadryl. Nicotine at the same time as Benadryl negates the drowsiness.
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