Viewing a single comment thread. View all comments

[deleted] OP t1_irb6590 wrote

Reply to comment by penicilling in Why do some antihistamines make you sleepy? by [deleted]

[removed]

1

[deleted] OP t1_irb6kxi wrote

[removed]

42

[deleted] OP t1_irb6ppd wrote

[removed]

1

[deleted] OP t1_irb7e92 wrote

[removed]

11

penicilling t1_irbasko wrote

>Are 1st gen safer ? wich do you reccommend ?

While I cannot recommend a specific medication for anyone (an interview, physical exam, and review of current and past medical issues is necessary before any such recommendations), in general, second-generation antihistamines such as cetirizine, fexofenadine, and loratadine are the first-line recommendations for symptoms of allergic rhinitis, as the side effects (such as sedation) are much less pronounced than the first-generation medications.

8

[deleted] OP t1_irbg8ou wrote

[deleted]

2

penicilling t1_irbn6c0 wrote

>Not just that, the second generation antihistamines are generally first line for anything where an actual antihistamine would be required,

This is generally true. The exception would be in patients for whom oral medications are not optimal, such as those with nausea and vomiting or with severe allergic reactions -- some 1st generation antihistamines are available in parenteral formulations, whereas, to the best of my knowledge, 2nd generation antihistamines are only available in oral form.

3

GamblingTheory t1_irbk18u wrote

Fexofenadine is a third generation antihistamine and thus in many countries not freely available without prescription.

1

The_RealKeyserSoze t1_irb9ouf wrote

There are pros and cons with any medication, best to consult a doctor about your specific condition/use case.

5

Schip92 t1_irb9z4b wrote

Yeah I know , I use cetirizine and acupuncture :) Normally If I do multiple sets od acupuncture I don't use pharmaceuticals

−2

cardew-vascular t1_irbqu6d wrote

2nd generation is safer because they don't break the blood brain barrier but 1st generation are still more effective for most people for the very same reason.

That's why I have both Benedryl and prescription Citirizine at home, Citirizine to take on the daily (40mvg 2x daily during allergy season or 8 extra strength reactine a day) to try to deal and Benedryl for when things get bad and I have no other plans.

3

celestiaequestria t1_irbk84s wrote

No, absolutely not. Newer antihistamines are recommended over older drugs like diphenhydramine. Benadryl can cause cardiac events, not to mention being a deliriants that is often given to children in overly large doses. Long-term use is also concerning given their correlation with dementia.

2

zachtheperson t1_irboax1 wrote

Small correction, not a dissociative, but a deliriant. Deliriants tend to be a much worse experience

2