Reisevi3ber t1_jclq4q5 wrote
Reply to comment by supapoopascoopa in Are there any known endogenous retroviruses that can cause active infections, and is this possible in principle? by amlyo
Which ones can cause autoimmune diseases and cancers?
Uncynical_Diogenes t1_jcm6cq8 wrote
“Which ones” is probably not a super stellar question because they probably have quite boring technical names, and the list of ones we actually have found and named is likely much smaller than the list of potential causative agents.
References 4-7 of the linked text:
> 4. Boller K, Konig H, Sauter M, et al. Evidence that HERV-K is the endogenous retrovirus sequence that codes for the human teratocarcinoma-derived retrovirus HTDV. Virology 1993;196:349–53. [PubMed] [Google Scholar]
>5. Lower R, Boller K, Hasenmaier B, et al. Identification of human endogenous retroviruses with complex mRNA expression and particle formation. Proc Natl Acad Sci U S A 1993;90:4480–4. [PMC free article] [PubMed] [Google Scholar]
>6. Nelson PN. Retroviruses in rheumatic diseases. Ann Rheum Dis 1995;55:441–2. [PMC free article] [PubMed] [Google Scholar]
>7. Nelson PN, Lever AML, Smith S, et al. Molecular investigations implicate human endogenous retroviruses as mediators of anti-retroviral antibodies in autoimmune rheumatic disease. Immunol Invest 1999;28:277–89. [PubMed] [Google Scholar]
Some rheumatic conditions and at least one cancer have been at least linked to expression of human ERV’s, if not necessarily the causative agents of such.
[deleted] t1_jcn1de8 wrote
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