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Rather_Dashing t1_jcylf94 wrote

Chromosome number is just one measure of compatibility and its not a particularly good one. Some species have wildly different chromosome numbers within the same species and yet breed fine. Plenty of pairs of species with the same number of chromosomes can't breed.

All you can really say is that chromosomal number differences and rearrangements tends to reduce the fitness of offspring and reduces the likelihood of fertile offspring.

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DrBarry_McCockiner t1_jcyt2z8 wrote

true enough, although it is a bit simplistic to say "Plenty of pairs of species with the same number of chromosomes can't breed" Generally if they are in the same genus and often the same family and have the same number of chromosome pairs, they can have offspring. Obviously, a reptile and a mammal with the same number of chromosomes will not be able to have offspring.

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