ceapaire t1_j7cex77 wrote on February 5, 2023 at 7:31 PM

Reply to comment by Cleistheknees in Did the 2009 H1N1 outbreak in the US increase the incidence of type 1 diabetes in adolescents? by legendary_kazoo

I was repeating what I was told by Dr.s in a research study I was in for T1D.

>There is no evidence to support this, at all, and quite a bit against it. The penetration of genes implicated in T1D is low. The concordance rate in monozygotic twins is low. 90% of people with T1D have no known relatives with the disease. Etc.

They also provided me with This study that says there's likely a genetic component since identical twins as well as non-identical if one has multiple of the antibodies. And it at least held enough weight for TrialNet to expand their testing for twins to lifetime instead of cutting it off at 18, as they do with any other relatives.

Cleistheknees t1_j7cgenh wrote on February 5, 2023 at 7:41 PM

To reiterate, if you’re saying “X is Y”, and it’s only true 30% of the time, then the statement is incorrect.

> They also provided me with This study that says there’s likely a genetic component since identical twins as well as non-identical if one has multiple of the antibodies.

There is most certainly a genetic component to autoimmune type 1 diabetes. That much is beyond question. However, you did say quite a bit more than “there’s a genetic component”.