We have a mid-1800's house with just two adults and we both work from home most of the time.

Primary family room is separate from the main house. We keep it 66 when we are using it, 54 when we are not. Heated by LP gas stove (Jotul Sebago)

Main house is 60 during the day and drops to 54 at night. Heated by heating oil and radiators. Three zones. We'll bump the heat to 65 as needed.

Bedroom's heat is managed by the main house heat but we have a 1500 watt electric heater in there and will set temp to 64 at night when we need it...most of the time we don't and it's in the mid to upper 50's.