Yeah. It always messed up my work in clinical drug manufacturing. We shut down for the week between xmas and new years, because everyone always wanted to take it off anyways (usually 23 Dec to 02 Jan we didn't work). But the week before and after we were always super busy to make sure we had enough stuff in stock, or catch up on stock because drug shipments still went out. We always had people take off the week before or after so they could have 2 weeks off straight. Even though it was only 3 people at a time, it would fuck us over pretty bad.