This actually happened, sort of, in Sheridan’s play « The Rivals ».

When it was performed the first night, the actor playing Sir Lucius O’Trigger was booed, and yelled to the audience « By the pow'rs, is it personal? — is it me, or the matter? », meaning «  Are you booing my character, or my performance? ». Unluckily for him, it was both. Sheridan rewrote the play and also replaced the actor for the next performance.