Fantastic question- here's an in-depth explanation of how the core mechanics function. After the intro the player has 3 statistics to manage- Hope, Hunger, and Health. The game is broken up to semi linear exploratory sidescrolling environments with items to find, and then a story moment, and then a campfire to rest at. The exploratory areas have items like food and medicine to find to increase your hunger mostly, but also have dangers that can hurt Dante. The most common of which is falling of the map, which generates a random "story moment" where you're spawned at the start of the level and Dante is given a health or hope debuff. The story moments are either a medical or ethical emergency, which Dante can usually approach from a couple of different perspectives. There's sometimes a medical RPG style interaction to represent Dante's treatment. The core of the game is here- almost always the most moral option will notably leave Dante weaker in some way. For instance- if Dante tries to interfere with an execution, he can just get shot and take a major health debuff. If Dante tries to treat a man with a highly infectious repository illness then Dante might catch it and have a status debuff for the rest of the game he needs to manage. Dante can be genuinely crippled at points too which reduces his efficacy as a doctor. All of this creates a desperate, edge of your seat moral thriller which will leave you earnestly thinking about your choices. (Once Dante reaches a campfire his health is adjusted proportionally to his hunger, and his hunger increases, then this cycle starts again.)