dangerWW t1_iww6uml wrote on November 18, 2022 at 8:31 PM

My sister has a genetic condition and is worried about getting pregnant and passing it to her child. Is there any fertility treatment that can help her?

DrJosephDavisDO OP t1_iww883w wrote on November 18, 2022 at 8:40 PM

Hi u/dangerWW,

I am sorry to hear about your sister's situation. The best advances in fertility treatments have been in the field of pre-implantation genetic testing (PGT). Using IVF, embryos can be tested safely for specific genetic conditions and then the unaffected embryos can be selected to have a baby without the condition. This is something many clinics including my own specialize in. Looking at my own clinic's data, we have a >85% pregnancy rate using PGT, so this is a very successful option to consider.

sqic80 t1_iwx1ypn wrote on November 19, 2022 at 12:18 AM

What’s your live birth rate? In the end, that the most important number.

DrJosephDavisDO OP t1_iwxn3z0 wrote on November 19, 2022 at 3:16 AM

Hi @sqic80,

Yes live birth rate is very important. With single euploid embryo transfers our current live birth rate averages 74% over the year.

doingallthething t1_iwx29af wrote on November 19, 2022 at 12:20 AM

Here is a medically reviewed article that you could share with your sister. Also, a lot of people with genetic concerns opt to use donor eggs or donor embryos, so they don't have to worry about passing that genetic concern on. But this article is a good place to start! https://www.fertilitywise.com/research/preimplantation-genetic-testing-pgt