Viewing a single comment thread. View all comments

cucciaman OP t1_itw9eud wrote

Reply to comment by wise-areola-fungus in We're a group of people with gut health issues, microbiome researchers, and physicians here to answer your questions on the gut microbiome and digestive health (IBS, IBD, and more). Ask us anything! by cucciaman

Thanks for the questions! I can give you some more information on your first question regarding the gut microbiome and acne.

The gut microbiome is an important regulator of the body’s immune system. In people with an altered, or dysbiotic, gut microbiome the permeability of the intestinal wall is increased. The increased permeability leads to the release of inflammatory compounds signalling and increase in inflammation throughout the body. This can lead to an increased response to bacteria on the skin and the development of acne. In addition, there can be alterations in the skin microbiome due to transit of bacteria from the gut to the skin, with the altered skin microbiome leading to the development of acne.
-RM

3