Barring a civilization-ending catastrophe, we will live longer and population will level off. No idea how longer. In the relatively near-term, we will solve the energy transformation from fossil fuels and be able to stabilize climate change. The universe is full of energy; we just have to wean ourselves off fossil fuels. We will have self-sufficient outposts throughout the solar system. Perhaps we will even begin terraforming a planet or moon or come up with a way to make interstellar travel possible. We will bring back newly-extinct species. Robots and AI will change the nature of society and work. All these are easy predictions, just as many of us could see the coming of the internet and beyond as soon as two computers were networked together. We could be heading towards a utopia or a dystopia. The biggest danger to us all is a slide back towards ignorance, especially if all the hard mental work is programmed away. The biggest challenges will be social and geopolitical, not technological. Beyond the next 100 years, no idea how much things will change.