The following submission statement was provided by /u/Ezekiel_W:

>Two major studies published in Nature have uncovered a new level of control of cancer gene activity within tumors, termed cancer's "dark matter."
>
>The revelation shows that epigenetics, cells controlling gene activity, play a crucial role in the development of cancer. Cancers are usually tested for DNA mutations alone, which can miss this level of control, thereby failing to predict how cancers may behave and respond to treatment.

Please reply to OP's comment here: https://old.reddit.com/r/Futurology/comments/yevfv6/major_breakthrough_in_cancer_research_papers/iu03gra/