Ocean_Soapian t1_isco7mm wrote on October 14, 2022 at 11:09 PM

Reply to comment by ThomasFromOhio in AI Can Offer Insight Into Who Responds to Antidepressants. A new algorithm predicts response to Sertraline with 83 percent accuracy. by Sariel007

They do. I took a test called Genesight. It breaks up the medications into three groups based how how well your body metabolizes them. Once I got that test, both meds I started were absolutely perfect. It's like I have a new life.

empteevessel t1_isk26gx wrote on October 16, 2022 at 4:06 PM

I took it too, albeit many years too late in my opinion. Results made so much sense, learned I had a moderate or sever gene interaction with all but 6 of the 20 some odd antidepressants listed in their panel. These pharmacogenomic tests shouldn’t be such a damn secret, would save years of trial and error for so many people.

Ocean_Soapian t1_isld0mv wrote on October 16, 2022 at 9:05 PM

Yeah, I had mine done at age 33.

I try hard not to become too caught up in my regret and sadness over not having the test available to me sooner. Almost no professional medical doctors know about it now, so it's not like I could have gotten it done in time to save all the years of agony over having severe MTHFR and not being medicated properly when i was younger. I would have had a much easier time in school, and in life in general.

But, I can't tell you how relieved I am to know that I'm not just lazy or useless, and that there was a legitimate medical reason for why doing things that seemed so easy for everyone else was so difficult for me.

I'm just very thankful that I've got another 30 or so years ahead of me where I get to have a better, more normal life experience. It makes me sad for those in the past that didn't have an explanation or a cure as to why they struggled so hard.

ThomasFromOhio t1_iso16nz wrote on October 17, 2022 at 12:40 PM

That's great to know but I wonder why it isn't more commonly performed. Wonder if it's $$$?

Ocean_Soapian t1_isp6e69 wrote on October 17, 2022 at 5:45 PM

It's expensive, but I don't think that's the reason why. Almost no general practitioners know about the test, or what MTFHR is. I think it's just still too unknown.